Cortical Amyloid beta in cognitively normal elderly adults is associated with decreased network efficiency within the cerebro-cerebellar system.

Cortical Amyloid beta in cognitively normal elderly adults is associated with decreased network efficiency within the cerebro-cerebellar system.

Deposition of cortical amyloid beta (Aβ) is a correlate of aging and a risk factor for Alzheimer Disease (AD). While several higher order cognitive processes involve functional interactions between cortex and cerebellum, this study aims to investigate effects of cortical Aβ deposition on coupling wi...

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Bibliographic Details
Main Authors: Stefanie eSteininger, Xinyang eLiu, Anton eGietl, Michael eWyss, Simon eSchreiner, Esmeralda eGruber, Valerie eTreyer, Andrea eKälin, Sandra eLeh-Seal, Alfred eBuck, Roger M Nitsch, Klaas P Prüssmann, Christoph eHock, Paul Gerson Unschuld
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer Disease
Amyloid beta-Peptides
Cerebellum
functional connectivity
aging neuroscience
fMRI BOLD
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00052/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00052/full

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