Cyclic mechanical strain with high-tensile triggers autophagy in growth plate chondrocytes

Cyclic mechanical strain with high-tensile triggers autophagy in growth plate chondrocytes

Abstract Background Mechanical loading has been widely considered to be essential for growth plate to maintain metabolism and development. Cyclic mechanical strain has been demonstrated to induce autophagy, whereas the relationship between cyclic tensile strain (CTS) and autophagy in growth plate ch...

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Bibliographic Details
Main Authors: Jin-ming Zhang, Zheng-gang Wang, Zhi-yi He, Liang Qin, Jiang Wang, Wen-tao Zhu, Jun Qi
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Cyclic tensile strain
Chondrocytes
Autophagy
Cytochalasin D
Online Access:https://doi.org/10.1186/s13018-022-03081-w

Internet

https://doi.org/10.1186/s13018-022-03081-w

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