Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus

Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus

Objective. This study was aimed at investigating whether sevoflurane inhalation induced cognitive impairment in rats with a possible mechanism involved in the event. Methods. Thirty-two rats were randomly divided into four groups of normal saline (NS) + O2, NS + sevoflurane (sevo), amyloid-β peptide...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Yue Tian, Ke-yan Chen, Li-dan Liu, Yun-xia Dong, Ping Zhao, Shan-bin Guo
Format:	Artikel
Sprache:	English
Veröffentlicht:	Wiley 2018-01-01
Schriftenreihe:	Mediators of Inflammation
Online Zugang:	http://dx.doi.org/10.1155/2018/3802324

Ähnliche Einträge

Therapeutic effects of intravenous administration of bone marrow stromal cells on sevoflurane-induced neuronal apoptosis and neuroinflammation in neonatal rats
von: ZhongLiang Sun, et al.
Veröffentlicht: (2015-08-01)

20- Deoxyingenol attenuate morphine-induced hippocampus neurotoxicity and memory impairments in rats
von: Jianfeng Ma, et al.
Veröffentlicht: (2024-06-01)

Impact of levetiracetam on cognitive impairment, neuroinflammation, oxidative stress, and neuronal apoptosis caused by lipopolysaccharides in rats
von: Vasudevan Mani, et al.
Veröffentlicht: (2023-09-01)

β2-Microglobulin exacerbates neuroinflammation, brain damage, and cognitive impairment after stroke in rats
von: Feng Chen, et al.
Veröffentlicht: (2023-01-01)

Sevoflurane induces endoplasmic reticulum stress mediated apoptosis in hippocampal neurons of aging rats.
von: Gang Chen, et al.
Veröffentlicht: (2013-01-01)

Resveratrol ameliorates neuronal apoptosis and cognitive impairment by activating the SIRT1/RhoA pathway in rats after anesthesia with sevoflurane
von: Qiaoyun Zhou, et al.
Veröffentlicht: (2022-02-01)

The effect of silver nanoparticles on apoptosis and dark neuron production in rat hippocampus
von: Farzaneh Bagheri-abassi, et al.
Veröffentlicht: (2015-07-01)

The neuron-astrocyte-microglia triad in normal brain ageing and in a model of neuroinflammation in the rat hippocampus.
von: Francesca Cerbai, et al.
Veröffentlicht: (2012-01-01)

Inhibitory neuron map of sevoflurane induced neurotoxicity model in young primates
von: Yixuan Niu, et al.
Veröffentlicht: (2023-10-01)

CHANGES IN THE NEURONAL ARCHITECTURE OF THE HIPPOCAMPUS IN A 6-OHDA-LESIONED HEMIPARKINSONIAN RAT MODEL, INDEPENDENTLY OF NEUROINFLAMMATION
von: Bohye Kim, et al.
Veröffentlicht: (2023-10-01)

Restoration of Proresolution Pathway with Exogenous Resolvin D1 Prevents Sevoflurane-Induced Cognitive Decline by Attenuating Neuroinflammation in the Hippocampus in Rats with Type 2 Diabetes Mellitus
von: Qingmei Sun, et al.
Veröffentlicht: (2021-07-01)

Allicin alleviates the decline in the learning ability and neuronal apoptosis in hippocampus of OSAHS model rats
von: WANG Chao, GENG Cai-hong, ZHAO Kun-peng, JI Peng
Veröffentlicht: (2022-10-01)

Effect of Ouabain on Glutamate Transport in the Hippocampus of Rats with LPS-Induced Neuroinflammation
von: Israel José Pereira Garcia, et al.
Veröffentlicht: (2023-03-01)

The Mechanisms of Sevoflurane-Induced Neuroinflammation
von: Xiangfei Huang, et al.
Veröffentlicht: (2021-08-01)

Sevoflurane induces inflammation of microglia in hippocampus of neonatal rats by inhibiting Wnt/β-Catenin/CaMKIV pathway
von: Fengjuan Wang, et al.
Veröffentlicht: (2021-06-01)

Dexmedetomidine protects the developing rat brain against the neurotoxicity wrought by sevoflurane: role of autophagy and Drp1–Bax signaling
von: Shan Y, et al.
Veröffentlicht: (2018-10-01)

Neuroinflammation in Bilirubin Neurotoxicity
von: Fanhui Zhang, et al.
Veröffentlicht: (2023-01-01)

Diquat exacerbates oxidative stress and neuroinflammation by blocking the autophagic flux of microglia in the hippocampus
von: Ping Wang, et al.
Veröffentlicht: (2024-11-01)

Dl-3-n-butylphthalide inhibits phenytoin-induced neuronal apoptosis in rat hippocampus and cerebellum
von: Junmin Chen, Na Liu, Xiaopeng Wang, Yanying Zhao, Junna He, Lan Yang, Qian Sun, Jing Zhao, Linjing Wang, Lei Chen
Veröffentlicht: (2019-09-01)

The effects of nano-silver and garlic administration during pregnancy on neuron apoptosis in rat offspring hippocampus
von: Maryam Lale Ataei, et al.
Veröffentlicht: (2014-06-01)

Sulforaphane Prevents Neuronal Apoptosis and Memory Impairment in Diabetic Rats
von: Gengyin Wang, et al.
Veröffentlicht: (2016-08-01)

High-fat diet exacerbated motor dysfunction via necroptosis and neuroinflammation in acrylamide-induced neurotoxicity in mice
von: Yalong Qiang, et al.
Veröffentlicht: (2024-01-01)

ApoE transiently regulates hippocampus amyloid‐beta deposition to stable learning and memory ability in adult rats exposed in sevoflurane
von: Shan Xu, et al.
Veröffentlicht: (2021-06-01)

PARP9 exacerbates apoptosis and neuroinflammation via the PI3K pathway in the thalamus and hippocampus and cognitive decline after cortical infarction
von: Mengshi Liao, et al.
Veröffentlicht: (2025-02-01)

The Role of the SIRT1-mTOR Signaling Pathway in Regulating Autophagy in Sevoflurane-Induced Apoptosis of Fetal Rat Brain Neurons
von: Yihui Li, et al.
Veröffentlicht: (2024-09-01)

Methamphetamine neurotoxicity, microglia, and neuroinflammation
von: Fatemeh Shaerzadeh, et al.
Veröffentlicht: (2018-12-01)

Sevoflurane exposure in early life: mitochondrial dysfunction and neurotoxicity in immature rat brains without long-term memory loss
von: Lin Qiu, et al.
Veröffentlicht: (2024-11-01)

Unraveling the signaling network between dysregulated microRNA and mRNA expression in sevoflurane-induced developmental neurotoxicity in rat
von: Yuanyuan Wang, et al.
Veröffentlicht: (2024-07-01)

Chronic neuroinflammation impairs waste clearance in the rat brain
von: Swathi Suresh, et al.
Veröffentlicht: (2022-12-01)

Effects of sevoflurane on neuronal cell damage after severe cerebral ischemia in rats
von: Hee-Pyoung Park, et al.
Veröffentlicht: (2020-02-01)

Role of α7nAChR-NMDAR in sevoflurane-induced memory deficits in the developing rat hippocampus.
von: XiaoHong Tang, et al.
Veröffentlicht: (2018-01-01)

Genome-Wide Screen of the Hippocampus in Aged Rats Identifies Mitochondria, Metabolism and Aging Processes Implicated in Sevoflurane Anesthesia
von: Yujie Wang, et al.
Veröffentlicht: (2020-05-01)

Sevoflurane Impairs Short-Term Memory by Affecting PSD-95 and AMPA Receptor in the Hippocampus of a Mouse Model
von: Yuan Jiao, et al.
Veröffentlicht: (2019-01-01)

Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity
von: Zhang Yibing, et al.
Veröffentlicht: (2020-06-01)

Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery.
von: Yuan Le, et al.
Veröffentlicht: (2014-01-01)

TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
von: Jayaraman, Anusha, et al.
Veröffentlicht: (2021)

TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
von: Anusha Jayaraman, et al.
Veröffentlicht: (2021-09-01)

Glibenclamide ameliorates the expression of neurotrophic factors in sevoflurane anaesthesia-induced oxidative stress and cognitive impairment in hippocampal neurons of old rats
von: Ma Yan, et al.
Veröffentlicht: (2021-12-01)

Cordycepin exacerbates cadmium-induced neurotoxicity via promoting endoplasmic reticulum stress-associated apoptosis
von: Ke Du, et al.
Veröffentlicht: (2022-02-01)

Acetylcholinesterase inhibitors reduce neuroinflammation and -degeneration in the cortex and hippocampus of a surgery stress rat model.
von: Alexander Kalb, et al.
Veröffentlicht: (2013-01-01)