Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous meningitis in a high burden setting: a prospective study.

Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous meningitis in a high burden setting: a prospective study.

Tuberculous meningitis (TBM) is difficult to diagnose promptly. The utility of the Xpert MTB/RIF test for the diagnosis of TBM remains unclear, and the effect of host- and sample-related factors on test performance is unknown. This study sought to evaluate the sensitivity and specificity of Xpert MT...

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Bibliographic Details
Main Authors: Vinod B Patel, Grant Theron, Laura Lenders, Brian Matinyena, Cathy Connolly, Ravesh Singh, Yacoob Coovadia, Thumbi Ndung'u, Keertan Dheda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC3805498?pdf=render

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http://europepmc.org/articles/PMC3805498?pdf=render

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