Affinity-based enrichment strategies to assay methyl-CpG binding activity and DNA methylation in early <it>Xenopus </it>embryos
<p>Abstract</p> <p>Background</p> <p>DNA methylation is a widespread epigenetic modification in vertebrate genomes. Genomic sites of DNA methylation can be bound by methyl-CpG-binding domain proteins (MBDs) and specific zinc finger proteins, which can recruit co-repress...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-08-01
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Series: | BMC Research Notes |
Online Access: | http://www.biomedcentral.com/1756-0500/4/300 |