Activation of Piezo1 contributes to matrix stiffness‐induced angiogenesis in hepatocellular carcinoma

Activation of Piezo1 contributes to matrix stiffness‐induced angiogenesis in hepatocellular carcinoma

Abstract Background Despite integrin being highlighted as a stiffness‐sensor molecule in matrix stiffness‐driven angiogenesis, other stiffness‐sensor molecules and their mechanosensory pathways related to angiogenesis in hepatocellular carcinoma (HCC) remain obscure. Here, we explored the interplay...

Full description

Bibliographic Details
Main Authors: Miao Li, Xi Zhang, Mimi Wang, Yaohui Wang, Jiali Qian, Xiaoxia Xing, Zhiming Wang, Yang You, Kun Guo, Jie Chen, Dongmei Gao, Yan Zhao, Lan Zhang, Rongxin Chen, Jiefeng Cui, Zhenggang Ren
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Cancer Communications
Subjects:
hepatocellular carcinoma
matrix stiffness
angiogenesis
Piezo1
HIF‐1α ubiquitination
Online Access:https://doi.org/10.1002/cac2.12364

Internet

https://doi.org/10.1002/cac2.12364

Similar Items