Urinary exosomes from patients with diabetic kidney disease induced podocyte apoptosis via microRNA-145-5p/Srgap2 and the RhoA/ROCK pathway

Urinary exosomes from patients with diabetic kidney disease induced podocyte apoptosis via microRNA-145-5p/Srgap2 and the RhoA/ROCK pathway

Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease without early diagnostic and specific therapeutic approaches. Podocyte apoptosis and loss play important roles in the pathological process of DKD. This study aimed to explore whether urinary exosomes from type 2 diabetes pat...

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Detalles Bibliográficos
Autores principales: Lulu Han, Shenghai Wang, Juan Li, Lulu Zhao, Hong Zhou
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2023-12-01
Colección:Experimental and Molecular Pathology
Materias:
Diabetic kidney disease
Urinary exosomes
MicroRNA-145-5p
Srgap2
ROCK
Podocyte apoptosis
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S001448002300028X

Internet

http://www.sciencedirect.com/science/article/pii/S001448002300028X

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