INCREASED EXPRESSION LEVEL OF ADAPTOR PROTEIN Ruk/CIN85 IN DOXORUBICIN-RESISTANT HUMAN NON-SMALL LUNG ADENOCARCINOMA MOR CELLS IS ASSOCIATED WITH THEIR METABOLIC REPROGRAMMING

INCREASED EXPRESSION LEVEL OF ADAPTOR PROTEIN Ruk/CIN85 IN DOXORUBICIN-RESISTANT HUMAN NON-SMALL LUNG ADENOCARCINOMA MOR CELLS IS ASSOCIATED WITH THEIR METABOLIC REPROGRAMMING

The aim of the present study was to find out the role of Ruk/CIN85 in modulation of activities/content of key enzymes/components of glycolysis and hydrogen peroxide using as a model human NSCLC MOR wild type and resistant to drugs MOR/0.2R cells. Materials and methods. MOR (ECACC 84112312) and M...

Full description

Bibliographic Details
Main Authors: Y.S.RAYNICH, T.D. SKATERNA, D.S. GERASHENKO, O. O. HUDKOVA, T. O. KISHKO, N. V. LATYSHKO
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2023-04-01
Series:Biotechnologia Acta
Subjects:
non-small-cell lung carcinoma (nsclc)
adaptor protein ruk/cin85
chemoresistance
metabolome reprogramming
metabolic enzymes
hydrogen peroxide
Online Access:https://biotechnology.kiev.ua/images/BTA/2023/2_2023/Raynich_2_2023.pdf

Internet

https://biotechnology.kiev.ua/images/BTA/2023/2_2023/Raynich_2_2023.pdf

Similar Items