Targeting the Endothelin-1 pathway to reduce invasion and chemoresistance in gallbladder cancer cells

Targeting the Endothelin-1 pathway to reduce invasion and chemoresistance in gallbladder cancer cells

Abstract Background Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma, often diagnosed at advanced stages with limited treatment options. The 5-year survival rate varies widely from 4 to 60%, mainly due to differences in disease stage detection. With only a small fraction of...

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Bibliographic Details
Main Authors: Francisco Rodas, Jetzabel A. Vidal-Vidal, Daniela Herrera, David A. Brown-Brown, Diego Vera, Joaquín Veliz, Pilar Püschel, José I. Erices, Verónica Sánchez Hinojosa, Julio C. Tapia, Eduardo Silva-Pavez, Claudia Quezada-Monrás, Pablo Mendoza-Soto, Flavio Salazar-Onfray, Cristian Carrasco, Ignacio Niechi
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cancer Cell International
Subjects:
Gallbladder cancer
Endothelin-1
Cell invasion
Chemosensitivity
Therapeutic targeting
Online Access:https://doi.org/10.1186/s12935-023-03145-9

Internet

https://doi.org/10.1186/s12935-023-03145-9

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