Computational protein design: validation and possible relevance as a tool for homology searching and fold recognition.

<h4>Background</h4>Protein fold recognition usually relies on a statistical model of each fold; each model is constructed from an ensemble of natural sequences belonging to that fold. A complementary strategy may be to employ sequence ensembles produced by computational protein design. D...

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Bibliographic Details
Main Authors: Marcel Schmidt Am Busch, Audrey Sedano, Thomas Simonson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20463972/?tool=EBI