Total syntheses of the parvistemoline alkaloids enabled by stereocontrolled Ir/Pd-catalyzed allylic alkylation
Abstract The functionalized polycycle with densely contiguous tertiary stereocenters is a formidable challenge in synthesizing the parvistemoline family of Stemona alkaloids. We herein report their catalytic, asymmetric total syntheses in 13–14 steps from commercially available 2-(methoxycarbonyl)-p...
| Prif Awduron: | , , , , , , , |
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| Fformat: | Erthygl |
| Iaith: | English |
| Cyhoeddwyd: |
Nature Portfolio
2024-12-01
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| Cyfres: | Nature Communications |
| Mynediad Ar-lein: | https://doi.org/10.1038/s41467-024-55111-2 |