3D osteogenic differentiation of human iPSCs reveals the role of TGFβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes

3D osteogenic differentiation of human iPSCs reveals the role of TGFβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes

Abstract Although the formation of bone-like nodules is regarded as the differentiation process from stem cells to osteogenic cells, including osteoblasts and osteocytes, the precise biological events during nodule formation are unknown. Here we performed the osteogenic induction of human induced pl...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Shunsuke Kawai, Junko Sunaga, Sanae Nagata, Megumi Nishio, Masayuki Fukuda, Takeshi Kamakura, Liping Sun, Yonghui Jin, Satoko Sakamoto, Akira Watanabe, Shuichi Matsuda, Taiji Adachi, Junya Toguchida
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Nature Portfolio 2023-01-01
Sraith:Scientific Reports
Rochtain ar líne:https://doi.org/10.1038/s41598-023-27556-w

Ar líne

https://doi.org/10.1038/s41598-023-27556-w

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