Plasma p-cresol lowering effect of sevelamer in peritoneal dialysis patients: evidence from a Cross-Sectional Observational Study.

p-Cresol is a by-product of the metabolism of aromatic aminoacid operated by resident intestinal bacteria. In patients with chronic kidney disease, the accumulation of p-cresol and of its metabolite p-cresyl-sulphate causes endothelial dysfunction and ultimately increases the cardiovascular risk of...

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Bibliographic Details
Main Authors: Bruna Guida, Mauro Cataldi, Eleonora Riccio, Lucia Grumetto, Andrea Pota, Silvio Borrelli, Andrea Memoli, Francesco Barbato, Gennaro Argentino, Giuliana Salerno, Bruno Memoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3756054?pdf=render