Novel 4-Aroyl-3-alkoxy-2(5H)-furanones as Precursors for the Preparation of Furo[3,4-b][1,4]-diazepine Ring System

A general synthesis of tetronic acid derivatives, namely 4-aroyl-3-alkoxy-2(5H)-furanones, is achieved via the treatment of an anhydrous dimethylformamide (DMF) solution of 4-aroyl-3-hydroxy-2(5H)-furanones with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as base at -10-0°C, followed by the addition...

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Bibliographic Details
Main Authors: Adel Amer, Jeanette Bauer, Sven Hausner, Christian P. Librera, Hans Zimmer
Format: Article
Language:English
Published: MDPI AG 2003-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/8/10/735/