Relationship of an hRAD54 gene polymorphism (2290 C/T) in an Ecuadorian population with chronic myelogenous leukemia

Relationship of an hRAD54 gene polymorphism (2290 C/T) in an Ecuadorian population with chronic myelogenous leukemia

The hRAD54 gene is a key member of the RAD52 epistasis group involved in repair of double-strand breaks (DSB) by homologous recombination (HR). Thus, alterations of the normal function of these genes could generate genetic instability, shifting the normal process of the cell cycle, leading the cells...

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Dettagli Bibliografici
Autori principali:	César Paz-y-Miño, Andrés López-Cortés, María José Muñoz, Bernardo Castro, Alejandro Cabrera, María Eugenia Sánchez
Natura:	Articolo
Lingua:	English
Pubblicazione:	Sociedade Brasileira de Genética 2010-01-01
Serie:	Genetics and Molecular Biology
Soggetti:	cancer leukemia CML ALL hRAD54 2290 C/T polymorphism
Accesso online:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000400009

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