Predicting mortality among ischemic stroke patients using pathways-derived polygenic risk scores

Abstract We aim to determine whether ischemic stroke(IS)-related PRSs are also associated with and further predict 3-year all-cause mortality. 1756 IS patients with European ancestry were randomly split into training (n = 1226) and testing (n = 530) groups with 3-year post-event observations. Univar...

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Bibliographic Details
Main Authors: Jiang Li, Durgesh Chaudhary, Christoph J. Griessenauer, David J. Carey, Ramin Zand, Vida Abedi
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16510-x