The Nephrotoxin Puromycin Aminonucleoside Induces Injury in Kidney Organoids Differentiated from Induced Pluripotent Stem Cells

Kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD), which can progress to end stage renal disease (ESRD), are a worldwide health burden. Organ transplantation or kidney dialysis are the only effective available therapeutic tools. Therefore, in vitro models of kidne...

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Bibliographic Details
Main Authors: Lisa Nguyen, Wasco Wruck, Lars Erichsen, Nina Graffmann, James Adjaye
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/4/635