Synthesis and Preliminary Biological Evaluations of Fluorescent or 149Promethium Labeled Trastuzumab-Polyethylenimine

Background: Radioimmunotherapy utilize a targeting antibody coupled to a therapeutic isotope to target and treat a tumor or disease. In this study we examine the synthesis and cell binding of a polymer scaffold containing a radiotherapeutic isotope and a targeting antibody. Methods: The multistep sy...

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Bibliographic Details
Main Authors: Jonathan Fitzsimmons, Tapan Nayak, Cathy Cutler, Robert Atcher
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/4/1/1