ATXN3 promotes prostate cancer progression by stabilizing YAP

ATXN3 promotes prostate cancer progression by stabilizing YAP

Abstract Background Prostate cancer (PC) is the most common neoplasm and is the second leading cause of cancer-related deaths in men worldwide. The Hippo tumor suppressor pathway is highly conserved in mammals and plays an important role in carcinogenesis. YAP is one of major key effectors of the Hi...

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Bibliographic Details
Main Authors: Longxiang Wu, Zhenyu Ou, Peihua Liu, Cheng Zhao, Shiyu Tong, Ruizhe Wang, Yangle Li, Junbin Yuan, Minfeng Chen, Benyi Fan, Xiongbing Zu, Yongjie Wang, Jianing Tang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell Communication and Signaling
Subjects:
Prostate cancer
ATXN3
YAP
Stabilization
Ubiquitination
Online Access:https://doi.org/10.1186/s12964-023-01073-9

Internet

https://doi.org/10.1186/s12964-023-01073-9

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