Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum

Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum

Summary: Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The present work aims to decipher the mechanism of acti...

Полное описание

Библиографические подробности
Главные авторы:	Sameh Obeid, Eloisa Berbel-Manaia, Valérie Nicolas, Indira Dennemont, Julien Barbier, Jean-Christophe Cintrat, Daniel Gillet, Philippe M. Loiseau, Sébastien Pomel
Формат:	Статья
Язык:	English
Опубликовано:	Elsevier 2023-11-01
Серии:	iScience
Предметы:	Parasitology Drugs Cell biology
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2589004223022216

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