Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Birt–Hogg–Dubé syndrome (BHD) is an autosomal dominant disorder caused by germline mutations in the folliculin gene (FLCN) that result in the functional loss of the tumor suppressor folliculin. It is classically associated with cutaneous hamartomas, pulmonary cysts with spontaneous pneumothorax, and...

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Detalles Bibliográficos
Autores principales: Grant W. Jirka, Daniel S. Lefler, Jessica Russo, Babar Bashir
Formato: Artículo
Lenguaje:English
Publicado: Taylor & Francis Group 2023-12-01
Colección:Cancer Biology & Therapy
Materias:
birt–hogg–dubé syndrome
colorectal cancer
folliculin gene
flcn mutation
wnt signaling
Acceso en línea:http://dx.doi.org/10.1080/15384047.2023.2184153

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