Impact of DAXX and ATRX expression on telomere length and prognosis of breast cancer patients

Abstract Background Telomere stability is one of the hallmarks of cancer that promotes cellular longevity, the accumulation of genetic alterations, and tumorigenesis. The loss of death domain-associated protein (DAXX) and α-thalassemia/mental retardation X-linked protein (ATRX) plays a role in telom...

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Bibliographic Details
Main Authors: Marwa T. Hussien, Shimaa Shaban, Doaa F. Temerik, Shaaban R. Helal, Eman Mosad, Sahar Elgammal, Abeer Mostafa, Eman Hassan, Abeer Ibrahim
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:Journal of the Egyptian National Cancer Institute
Subjects:
Online Access:http://link.springer.com/article/10.1186/s43046-020-00045-1