Nuclear face of Tau: an inside player in neurodegeneration

Abstract Tau (Tubulin associated unit) protein is a major hallmark of Alzheimer’s disease (AD) and tauopathies. Tau is predominantly an axonal protein with a crucial role in the stabilization and dynamics of the microtubules. Since the discovery of Tau protein in 1975, research efforts were concentr...

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Bibliographic Details
Main Authors: Neelam Younas, Tayyaba Saleem, Abrar Younas, Inga Zerr
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-023-01702-x