Nuclear face of Tau: an inside player in neurodegeneration
Abstract Tau (Tubulin associated unit) protein is a major hallmark of Alzheimer’s disease (AD) and tauopathies. Tau is predominantly an axonal protein with a crucial role in the stabilization and dynamics of the microtubules. Since the discovery of Tau protein in 1975, research efforts were concentr...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-12-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40478-023-01702-x |