Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke

Introduction/Rationale: In chronic obstructive pulmonary disease (COPD), defective macrophage phagocytic clearance of cells undergoing apoptosis by efferocytosis may lead to secondary necrosis of the uncleared cells and contribute to airway inflammation. The precise mechanisms for this phenomenon re...

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Главные авторы: Patrick F. Asare, Hai B. Tran, Plinio R. Hurtado, Griffith B. Perkins, Phan Nguyen, Hubertus Jersmann, Eugene Roscioli, Sandra Hodge
Формат: Статья
Язык:English
Опубликовано: SAGE Publishing 2021-10-01
Серии:Therapeutic Advances in Respiratory Disease
Online-ссылка:https://doi.org/10.1177/17534666211039769