Comprehensive Analysis of 1-Year-Old Female Apolipoprotein E-Deficient Mice Reveals Advanced Atherosclerosis with Vulnerable Plaque Characteristics
Apolipoprotein E-knockout (<i>Apoe</i>-/-) mice constitute the most widely employed animal model of atherosclerosis. Deletion of <i>Apoe</i> induces profound hypercholesterolemia and promotes the development of atherosclerosis. However, despite its widespread use, the <i&g...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/25/2/1355 |