Poly-ADP-ribose polymerase (PARP) inhibitors and ovarian function

Poly-ADP-ribose polymerase (PARP) inhibitors and ovarian function

Poly-ADP-ribose polymerase (PARP) plays an important role in DNA damage detection and repair. PARP inhibitors (PARPi) are a novel class of targeted agents used widely in the treatment of female cancer patients with BRCA mutations, including younger patients. However, the impact of PARPi on ovarian f...

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Bibliographic Details
Main Authors: Jiajia Li, Qingchao Li, Lingyi Zhang, Songling Zhang, Yun Dai
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
PARP inhibitor
Ovarian function
Fertility
BRCA mutation
DNA repair
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222014172

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http://www.sciencedirect.com/science/article/pii/S0753332222014172

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