SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping

Sensing DNA bases by surface-enhanced Raman spectroscopy (SERS) in plasmonic nanopores has suffered from rapid flow through of molecules. Here, the authors attach DNA molecules to gold nanoparticles which, due to electro-plasmonic trapping, allow for controlled residence times and discrimination of...

Full description

Bibliographic Details
Main Authors: Jian-An Huang, Mansoureh Z. Mousavi, Yingqi Zhao, Aliaksandr Hubarevich, Fatima Omeis, Giorgia Giovannini, Moritz Schütte, Denis Garoli, Francesco De Angelis
Format: Article
Language:English
Published: Nature Portfolio 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13242-x