SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping
Sensing DNA bases by surface-enhanced Raman spectroscopy (SERS) in plasmonic nanopores has suffered from rapid flow through of molecules. Here, the authors attach DNA molecules to gold nanoparticles which, due to electro-plasmonic trapping, allow for controlled residence times and discrimination of...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-13242-x |
| _version_ | 1818992440395169792 |
|---|---|
| author | Jian-An Huang Mansoureh Z. Mousavi Yingqi Zhao Aliaksandr Hubarevich Fatima Omeis Giorgia Giovannini Moritz Schütte Denis Garoli Francesco De Angelis |
| author_facet | Jian-An Huang Mansoureh Z. Mousavi Yingqi Zhao Aliaksandr Hubarevich Fatima Omeis Giorgia Giovannini Moritz Schütte Denis Garoli Francesco De Angelis |
| author_sort | Jian-An Huang |
| collection | DOAJ |
| description | Sensing DNA bases by surface-enhanced Raman spectroscopy (SERS) in plasmonic nanopores has suffered from rapid flow through of molecules. Here, the authors attach DNA molecules to gold nanoparticles which, due to electro-plasmonic trapping, allow for controlled residence times and discrimination of single nucleotides. |
| first_indexed | 2024-12-20T20:26:12Z |
| format | Article |
| id | doaj.art-dbd9b53ffbea4edea77b7c3a88a2c37e |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T20:26:12Z |
| publishDate | 2019-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-dbd9b53ffbea4edea77b7c3a88a2c37e2022-12-21T19:27:28ZengNature PortfolioNature Communications2041-17232019-11-0110111010.1038/s41467-019-13242-xSERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trappingJian-An Huang0Mansoureh Z. Mousavi1Yingqi Zhao2Aliaksandr Hubarevich3Fatima Omeis4Giorgia Giovannini5Moritz Schütte6Denis Garoli7Francesco De Angelis8Istituto Italiano di TecnologiaIstituto Italiano di TecnologiaIstituto Italiano di TecnologiaIstituto Italiano di TecnologiaIstituto Italiano di TecnologiaIstituto Italiano di TecnologiaAlacris Theranostics GmbHIstituto Italiano di TecnologiaIstituto Italiano di TecnologiaSensing DNA bases by surface-enhanced Raman spectroscopy (SERS) in plasmonic nanopores has suffered from rapid flow through of molecules. Here, the authors attach DNA molecules to gold nanoparticles which, due to electro-plasmonic trapping, allow for controlled residence times and discrimination of single nucleotides.https://doi.org/10.1038/s41467-019-13242-x |
| spellingShingle | Jian-An Huang Mansoureh Z. Mousavi Yingqi Zhao Aliaksandr Hubarevich Fatima Omeis Giorgia Giovannini Moritz Schütte Denis Garoli Francesco De Angelis SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping Nature Communications |
| title | SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping |
| title_full | SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping |
| title_fullStr | SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping |
| title_full_unstemmed | SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping |
| title_short | SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping |
| title_sort | sers discrimination of single dna bases in single oligonucleotides by electro plasmonic trapping |
| url | https://doi.org/10.1038/s41467-019-13242-x |
| work_keys_str_mv | AT jiananhuang sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT mansourehzmousavi sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT yingqizhao sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT aliaksandrhubarevich sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT fatimaomeis sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT giorgiagiovannini sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT moritzschutte sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT denisgaroli sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping AT francescodeangelis sersdiscriminationofsinglednabasesinsingleoligonucleotidesbyelectroplasmonictrapping |