Retinal Tissue Shows Glial Changes in a Dravet Syndrome Knock-in Mouse Model

Retinal Tissue Shows Glial Changes in a Dravet Syndrome Knock-in Mouse Model

Dravet syndrome (DS) is an epileptic encephalopathy caused by mutations in the <i>Scn1a</i> gene encoding the α1 subunit of the Nav1.1 sodium channel, which is associated with recurrent and generalized seizures, even leading to death. In experimental models of DS, histological alteration...

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Bibliographic Details
Main Authors: Juan J. Salazar, Andrea Satriano, José A. Matamoros, José A. Fernández-Albarral, Elena Salobrar-García, Inés López-Cuenca, Rosa de Hoz, Lidia Sánchez-Puebla, José M. Ramírez, Cristina Alonso, Valentina Satta, Inés Hernández-Fisac, Onintza Sagredo, Ana I. Ramírez
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Dravet syndrome
retina
astrocytes
microglia
retinal ganglion cells
GABAergic amacrine cells
Online Access:https://www.mdpi.com/1422-0067/24/3/2727

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https://www.mdpi.com/1422-0067/24/3/2727

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