Therapeutic Response of miR-145 Micelles on Patient-Derived Vascular Smooth Muscle Cells

During atherosclerosis, vascular smooth muscle cells (VSMCs) undergo a phenotypic transition from a healthy contractile state into pathological phenotypes including a proliferative and migratory, synthetic phenotype and osteochondrogenic-like phenotype that exacerbate plaques. Thus, inhibiting the t...

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Bibliographic Details
Main Authors: Neil Patel, Deborah D. Chin, Gregory A. Magee, Eun Ji Chung
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Digital Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fdgth.2022.836579/full