Differential contribution of p300 and CBP to regulatory element acetylation in mESCs

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs

Abstract Background The transcription coactivators CREB binding protein (CBP) and p300 are highly homologous acetyltransferases that mediate histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and promoters. Although in most cases, CBP and p300 are considered to be fun...

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Bibliografiska uppgifter
Huvudupphovsmän: Sara Martire, Jennifer Nguyen, Aishwarya Sundaresan, Laura A. Banaszynski
Materialtyp: Artikel
Språk:English
Publicerad: BMC 2020-07-01
Serie:BMC Molecular and Cell Biology
Ämnen:
Enhancer
Chromatin
Acetyltransferase
Embryonic stem cell
Länkar:http://link.springer.com/article/10.1186/s12860-020-00296-9

Internet

http://link.springer.com/article/10.1186/s12860-020-00296-9

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