Deficiency of activation-induced cytidine deaminase in a murine model of ulcerative colitis

Patients with inflammatory bowel disease (IBD) have an increased risk of colorectal cancer, particularly in ulcerative colitis (UC) when the majority of colon epithelial cells may be exposed to inflammation-associated mutagenesis. In addition to mutagenesis generated by oxidative stress, inflammatio...

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Bibliographic Details
Main Authors: Laura P. Hale, Sebastian D. Fugmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498091/?tool=EBI