Pseudomonas Exotoxin A Based Toxins Targeting Epidermal Growth Factor Receptor for the Treatment of Prostate Cancer
The epidermal growth factor receptor (EGFR) was found to be a valuable target on prostate cancer (PCa) cells. However, EGFR inhibitors mostly failed in clinical studies with patients suffering from PCa. We therefore tested the targeted toxins EGF-PE40 and EGF-PE24mut consisting of the natural ligand...
Main Authors: | , , , , |
---|---|
Formato: | Artigo |
Idioma: | English |
Publicado em: |
MDPI AG
2020-11-01
|
Colecção: | Toxins |
Assuntos: | |
Acesso em linha: | https://www.mdpi.com/2072-6651/12/12/753 |