Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis
Abstract Background Sarcomas are a very heterogeneous group of tumors with intrinsic developmental programs derived from the cell of origin. This implies a functional hierarchy inside tumors governed by sarcoma stem cells. Therefore, genetic and/or epigenetic changes profoundly affect the biology of...
Main Authors: | , , , |
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格式: | 文件 |
语言: | English |
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BMC
2021-08-01
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丛编: | Journal of Experimental & Clinical Cancer Research |
主题: | |
在线阅读: | https://doi.org/10.1186/s13046-021-02048-9 |