Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis

Abstract Background Sarcomas are a very heterogeneous group of tumors with intrinsic developmental programs derived from the cell of origin. This implies a functional hierarchy inside tumors governed by sarcoma stem cells. Therefore, genetic and/or epigenetic changes profoundly affect the biology of...

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Main Authors: Manuel Pedro Jimenez-García, Antonio Lucena-Cacace, Daniel Otero-Albiol, Amancio Carnero
格式: 文件
语言:English
出版: BMC 2021-08-01
丛编:Journal of Experimental & Clinical Cancer Research
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在线阅读:https://doi.org/10.1186/s13046-021-02048-9