Preparation and Characterization of Spray-Dried Inhalable Powders Containing Polymeric Micelles for Pulmonary Delivery of Paclitaxel in Lung Cancer

Purpose: Local delivery of chemotherapeutic drugs to the lungs offers many advantages for lung cancer treatment compared to conventional systemic chemotherapy. In the present study, novel mixed polymeric micelles based on tocopheryl succinate-polyethylene glycol 1000 and 5000 Da (TPGS1K and TPGS5K)...

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Bibliographic Details
Main Authors: Mahboubeh Rezazadeh, Zahra Davatsaz, Jaber Emami, Farshid Hasanzadeh, Ali Jahanian-Najafabadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/30048