A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis
Objectives: There is an unmet medical need for biomarkers in OA which can be applied in clinical drug development trials. The present study describes the development of a specific and robust assay measuring type II collagen degradation (T2CM) and discusses its potential as a noninvasive translationa...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-12-01
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Series: | Osteoarthritis and Cartilage Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2665913121000704 |