A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15

Chemoattractants control lymphocyte recruitment from the blood, contributing to the systemic organization of the immune system. The G protein-linked receptor GPR15 mediates lymphocyte homing to the large intestines and skin. Here we show that the 9 kDa CC-motif containing cationic polypeptide AP57/c...

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Bibliographic Details
Main Authors: Borja Ocón, Junliang Pan, Theresa Thu Dinh, Wenjing Chen, Romain Ballet, Michael Bscheider, Aida Habtezion, Hua Tu, Brian A. Zabel, Eugene C. Butcher
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
T cells
trafficking receptor
GPR15
ligand
chemokine
colon
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01111/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01111/full

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