In vitro activity of apramycin against 16S-RMTase-producing Gram-negative isolates

In vitro activity of apramycin against 16S-RMTase-producing Gram-negative isolates

ABSTRACT: Objectives: Apramycin is an aminoglycoside (AG) with a unique structure that is little affected by plasmid-mediated mechanisms of AG resistance, including most AG-modifying enzymes and 16S rRNA methyltransferases (16S-RMTases). We evaluate the activity of apramycin against a collection of...

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Bibliographic Details
Main Authors: François Caméléna, Mathilde Liberge, Inès Rezzoug, Manel Merimèche, Thierry Naas, Béatrice Berçot
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Aminoglycosides
16S rRNA methyltransferases
ArmA
RmtB
AAC(3)-IV
Gram-negative bacilli
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716523000188

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http://www.sciencedirect.com/science/article/pii/S2213716523000188

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