Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity

Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity

Objectives: Diet-driven obesity is increasingly widespread. Its consequences pose major challenges to human health and health care systems. There are MAP kinase-interacting kinases (MNKs) in mice, MNK1 and MNK2. Studies have demonstrated that mice lacking either MNK1 or MNK2 were partially protected...

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Bibliographic Details
Main Authors: Lauren Y. Sandeman, Wan Xian Kang, Xuemin Wang, Kirk B. Jensen, Derick Wong, Tao Bo, Ling Gao, Jiajun Zhao, Christopher D. Byrne, Amanda J. Page, Christopher G. Proud
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Metabolism
Subjects:
Adipose tissue
Diet-induced obesity
MNK
Lipid metabolism
Mitochondria
Energy expenditure
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301289

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http://www.sciencedirect.com/science/article/pii/S2212877820301289

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