Discovery from Hypericum elatoides and synthesis of hyperelanitriles as α-aminopropionitrile-containing polycyclic polyprenylated acylphloroglucinols

Abstract The search for lead compounds with anti-neuroinflammatory activity from structurally ‘optimized’ natural products is a crucial and promising strategy in the quest to discover safe and efficacious agents for treating neurodegenerative diseases. A phytochemical investigation on the aerial por...

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Bibliographic Details
Main Authors: Jin-Yan Xie, Pengfei Li, Xi-Tao Yan, Jin-Ming Gao
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-023-01091-1