Structural and functional characterization of IgG- and non-IgG-based T-cell-engaging bispecific antibodies

Bispecific T-cell-engaging antibodies are a growing class of therapeutics with numerous molecules being tested in clinical trials and, currently, seven of them have received market approval. They are structurally complex and function as adaptors to redirect the cytotoxicity of T cells to kill tumor...

詳細記述

書誌詳細
主要な著者: Nishant Mohan, Safiat Ayinde, Hanjing Peng, Shraboni Dutta, Yi Shen, Vincent M. Falkowski, Thomas G. Biel, Tongzhong Ju, Wen Jin Wu
フォーマット: 論文
言語:English
出版事項: Frontiers Media S.A. 2024-05-01
シリーズ:Frontiers in Immunology
主題:
オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1376096/full