Surface modification of titanium substrate via combining photothermal therapy and quorum-sensing-inhibition strategy for improving osseointegration and treating biofilm-associated bacterial infection

Insufficient osseointegration and biofilm-associated bacterial infection are important challenges for clinical application of titanium (Ti)-based implants. Here, we constructed mesoporous polydopamine (MPDA) nanoparticles (NPs) loaded with luteolin (LUT, a quorum sensing inhibitor), which were furth...

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Bibliographic Details
Main Authors: Jingwei Hu, Yao Ding, Bailong Tao, Zhang Yuan, Yulu Yang, Kun Xu, Xuan Li, Peng liu, Kaiyong Cai
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-12-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2200127X