Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI

Summary: Glucocorticoid-induced osteoporosis (GIOP) is a severe and common complication of long-term usage of glucocorticoids (GCs) and lacks of efficient therapy. Here, we investigated the mechanism of anti-inflammation effect and osteoclastogenesis side effect of GCs and immunoglobulin G (IgG) tre...

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Bibliographic Details
Main Authors: Lijuan Jiang, Wenlin Qiu, Xuefei Wang, Xiaoru Duan, Xiaoxiao Han, Tong Yu, Shenghui Wen, Zhijun Luo, Ruizhi Feng, Yao Teng, Haifeng Yin, Christian M. Hedrich, Guo-Min Deng
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018266