Attenuated and protease-profile modified sendai virus vectors as a new tool for virotherapy of solid tumors.

Attenuated and protease-profile modified sendai virus vectors as a new tool for virotherapy of solid tumors.

Multiple types of oncolytic viruses are currently under investigation in clinical trials. To optimize therapeutic outcomes it is believed that the plethora of different tumor types will require a diversity of different virus types. Sendai virus (SeV), a murine parainfluenza virus, displays a broad h...

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Bibliographic Details
Main Authors: Martina Zimmermann, Sorin Armeanu-Ebinger, Sascha Bossow, Johanna Lampe, Irina Smirnow, Andrea Schenk, Sebastian Lange, Thomas S Weiss, Wolfgang Neubert, Ulrich M Lauer, Michael Bitzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090508&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090508&type=printable

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