Subclonal heterogeneity and evolution in breast cancer

Abstract Subclonal heterogeneity and evolution are characteristics of breast cancer that play a fundamental role in tumour development, progression and resistance to current therapies. In this review, we focus on the recent advances in understanding the epigenetic and transcriptomic changes that occ...

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Bibliographic Details
Main Authors: Ioanna Mavrommati, Flora Johnson, Gloria V. Echeverria, Rachael Natrajan
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00363-0