PA-MSHA induces inflamed tumor microenvironment and sensitizes tumor to anti-PD-1 therapy

PA-MSHA induces inflamed tumor microenvironment and sensitizes tumor to anti-PD-1 therapy

Abstract A low response rate to immune checkpoint inhibitor (ICI) therapy has impeded its clinical use. As reported previously, an inflamed tumor microenvironment (TME) was directly correlated with patients’ response to immune checkpoint blockade (ICB). Thus, restoring the cytotoxic effect of immune...

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Bibliographic Details
Main Authors: Min Huang, Fang He, Dan Li, Ya-Jia Xie, Ze-Bo Jiang, Ju-Min Huang, Xiao-Ping Zhao, Ali Adnan Nasim, Jun-Hui Chen, Jin-Cai Hou, Xian-Ming Fan, Elaine Lai-Han Leung, Xing-Xing Fan
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05368-6

Internet

https://doi.org/10.1038/s41419-022-05368-6

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