Synthesis of Novel Conjugated Linoleic Acid (CLA)-Coated Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for the Delivery of Paclitaxel with Enhanced In Vitro Anti-Proliferative Activity on A549 Lung Cancer Cells

Synthesis of Novel Conjugated Linoleic Acid (CLA)-Coated Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for the Delivery of Paclitaxel with Enhanced In Vitro Anti-Proliferative Activity on A549 Lung Cancer Cells

The application of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) as a nanomedicine for Non-Small Cell Lung Carcinoma (NSCLC) can provide effective delivery of anticancer drugs with minimal side-effects. SPIONs have the flexibility to be modified to achieve enhanced oading of hydrophobic antica...

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Bibliographic Details
Main Authors: Lindokuhle M. Ngema, Samson A. Adeyemi, Thashree Marimuthu, Philemon Ubanako, Daniel Wamwangi, Yahya E. Choonara
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
superparamagnetic iron oxide nanoparticles
non-small-cell lung carcinoma
A549 cell line
conjugated linoleic acid
paclitaxel
nanomedicine
Online Access:https://www.mdpi.com/1999-4923/14/4/829

Internet

https://www.mdpi.com/1999-4923/14/4/829

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