Examining the Association between Mitochondrial Genome Variation and Coronary Artery Disease

Large-scale genome-wide association studies have identified hundreds of single-nucleotide variants (SNVs) significantly associated with coronary artery disease (CAD). However, collectively, these explain <20% of the heritability. Hypothesis: Here, we hypothesize that mitochondrial (MT)-SNVs might...

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Bibliographic Details
Main Authors: Baiba Vilne, Aniket Sawant, Irina Rudaka
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/3/516