Effects of early-life 6:2 Cl-PFESA exposure on hippocampal AMPA receptor gene expression in offspring mice

Effects of early-life 6:2 Cl-PFESA exposure on hippocampal AMPA receptor gene expression in offspring mice

BackgroundThe compound 6:2 chlorinated polyfluorinated ether sulfonic acids (6:2 Cl-PFESA) has been demonstrated abilities of strong bioaccumulation and placental barrier penetration, and it can also cross the blood-brain barrier. However, the mechanism of its neurodevelopmental toxicity in offsprin...

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Bibliographic Details
Main Authors: Ruiwen WANG, Yaping YAO, Jingshuang CAI, Fulin QU, Xiaoxia JIN
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2024-05-01
Series:环境与职业医学
Subjects:
α-amino-3-hydroxy-5-methylisoxazole-4-propionic receptor
6:2 chlorinated polyfluorinated ether sulfonic acids
neurodevelopmental toxicity
synaptic plasticity
learning and memory
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM23356

Internet

http://www.jeom.org/article/cn/10.11836/JEOM23356

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