Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond

The recent FDA approval of the neurosteroid, brexanolone (allopregnanolone), as a treatment for women with postpartum depression, and successful trials of a related neuroactive steroid, SGE-217, for men and women with major depressive disorder offer the hope of a new era in treating mood and anxiety...

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Bibliographic Details
Main Authors: Charles F. Zorumski, Steven M. Paul, Douglas F. Covey, Steven Mennerick
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Neurobiology of Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289519300487